Time-lapse microscopy of derived rapid settling (left) and slow settling (right) genotypes isolated from 5 minute and 25 minute settling regimes, respectively. Cultures were grown for 24 h, diluted 300-fold, and grown in 0.5 uL YPD. Time-lapse microscopy was performed with images taken every minute for 600 minutes. (Ratcliff et al. 2011)