Professor
Dept. of Ecology, Evolution, & Behavior
BioTechnology Institute
Ph.D. Washington University, St. Louis, 1987
E-mail: deanx024@umn.edu
Research Interests
Molecular evolution, enzymology.
Recent Publications
Zhang, L, H Yang, M Long, L Li, AM Dean. 2010. Evolution of enzymatic activities of testis-specific short-chain 9dehydrogenase/reductase in Drosophila. J Mol Evol 71:241-249
Lunzer, M, GB Golding, AM Dean. 2010. Pervasive cryptic epistatis in molecular evolution. 6(10): e1001162. doi:10.1371/journal.pgen.1001162PLoS Genetics
Eshelman, C, R Vouk, JL Stewart, E Halsne, S Schneider, M Gualu, AM Dean, B Kerr. 2010. Unrestricted migration favors virulent pathogens in experimental metapopulations evolutionary genetics of a rapacious life history. 2503-2513 365:Philos Trans Roy Soc Lond B Biol Sci
Dean, AM. 2010. The future of molecular evolution. 11:409EMBO Reports
Zhang, B, B Wang, A Liu, J Hao, Z Cao, AM Dean, G Zhu. 2009. Enzymatic characterization of a monomeric isocitrate dehydrogenase from 9Streptomyces lividans TK54. 91:1405-1410Biochimie
Dykhuizen DE, AM Dean. 2009. Short term experimental evolution: from the bottom up. In: Experimental Evolution: Concepts, Methods, and Applications, pp 65-87. T Garland Jr, MR Rose, Eds. University of California Press, Berkeley, CA
Zhong S, SP Miller, DE Dykhuizen, AM Dean. 2009. Transcription, Translation and the Evolution of Specialists and Generalists. . 26:2661-2678.Mol Biol Evol
Stoebel DM, AM Dean, DE Dykhuizen. 2008. The cost of protein expression is in the process, not the product. 1653-1660178:Genetics
Dean AM & JW Thornton. 2007. Evolution and gene function: a new synthesis in molecular biology and evolution. 675-6888:Nat Rev Genet
Merlo LMF, M Lunzer & AM Dean. 2007. An empirical test of the concomitantly variable codon hypothesis. 104:10938-10942Proc Natl Acad Sci USA
Miller SP, M Lunzer & AM Dean. 2006. Direct demonstration of an adaptive constraint. 314:458-461Science
Kerr B, C Neuhauser, BJM Bohannan & AM Dean. 2006. Local migration promotes competitive restraint in a host-pathogen 'tragedy of the commons.' 442:75-78Nature
Merlo LMF, MJ Sadowsky, JA Ferguson & AM Dean. 2006. Selection and polymorphism at the argR locus of Escherichia coli. 376:240-247Gene
Lunzer M, SP Miller, R Felsheim & AM Dean. 2005. The biochemical architecture of an ancient adaptive landscape. 310:499-501Science
Suiter AM, & AM Dean. 2005. Selection in a seasonal environment: the impact of phenotypic lag on Darwinian fitness. 61:153-170J Mol Evol
Zhu G, GB Golding & AM Dean. 2005. The selective cause of an ancient adaptation. 1279-1282307:Science
Dean, AM. 2005. Protecting haploid polymorphisms in temporally variable environments. 169:1147-1156Genetics
Zhang J, AM Dean, F Brunet & M Long. 2004. Evolving protein functional diversity in new genes of Drosophila. 101:16246-16250Proc Natl Acad Sci USA
Zhong S, A Khodursky, DE Dykhuizen & AM Dean. 2004. Evolutionary genomics of ecological specialization. 101:11719-11724Proc Natl Acad Sci USA
Dykhuizen DE & AM Dean. 2004. Evolution of specialists in an experimental microcosm. 167:2015-2026.Genetics